Ramipril is a highly lipophilic, long acting ACE inhibitor. The drug is used for treating blood pressure and congestive heart failure. It effectively reduces both supine and standing blood pressure without significant alteration in the pulse rate.

Working
The drug acts by lowering the production of Angiotensin II, therefore relaxing arterial muscles while at the same time enlarging the arteries. The process allows the heart to pump blood easier, and increasing the blood flow due to more blood being pumped into and through bigger passageways.

Dosage
Hypertension: 2.5 mg/day, Max: 10mg /day.
Cardiac Failure: 1.25mg/day, increased to 2.5 mg once daily, Max:10mg/day

Contra- Indications: Hypersensitivity, bilateral renal artery stenosis, pregnancy, lactation.

Side Effects
The drug has certain side effects, that can affect individuals in different ways. The following are some of the side effects, that are often associated with the drug:

• Hypotension
• Renal impairment
• Cough
• Hyperkalemia

Brands