Loratidine is a new generation antihistamine drug, used for treating various skin and other allergies. Since the medicine does not cross the blood-brain barrier, so it also does not cause drowsiness. The drug has a much longer lasting effect when compared to other antihistamines in use.

It is (H1) receptor antagonist, penetrates very poorly into the central system, hence is devoid of CNS depressant effects. Structurally it is related to azatidine. Loratidine also suppresses mast cell mediator release.

Working
The drug acts by blocking the effects of histamine at peripheral H1 receptor sites; It also has anticholinergic (atropine-like) and antipruritic effects

Dosage
Adults: 10 mg once daily.
6-12 years: 5-10 mg once a day

Contra- Indications: Hypersensitivity, Pregnancy, Lactation

Side Effects
The drug has certain side effects, that can affect individuals in different ways. The following are some of the side effects, that are often associated with the drug:

• Nausea
• Fatigue
• Headache

Brands