Levocetrizine or levocetirizine is a selective, long acting peripheral H1 receptor antagonist antihistamine. The increased polarity of the drug may decrease distribution of the drug into the CNS, resulting in reduced potential for adverse CNS effects. Tolerance does not occur. As it does not readily cross the blood brain barrier, it does not cause sedation or interfere with mental alertness or memory function.

The drug is highly effective and well-tolerated anti-histamine, introduced for treating symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and chronic idiopathic urticaria.

Levocetrizine, a potent single isomer of cetrizine, binds twice as strongly to histamine H1 receptors in vitro and also has a highly consistent and predictable anti-histamine action.

Dosage
Adults & children above 6 years: 5mg single intake orally
Children below 6 years: No adjusted dose
Elderly: Adjust dose on the basis of renal function

Contra- Indications: In severe renal impairment

Side Effects
The drug has certain side effects, that can affect individuals in different ways. The following are some of the side effects, that are often associated with the drug:

• Headache
• Somnolence
• Dry mouth
• Mild Drowsiness

Use the drug with caution during pregnancy and lactation, as the drug may pass into the breast milk.

Brands