Domperidone is an antidopaminergic drug, that can either be used orally or intravenously, for suppressing nausea and vomiting. The drug has also been used for stimulating lactation.

Domperidone is a potent dopamine antagonist with antiemetic properties. It is useful in treatment of nausea, vomiting and dyspepsia. It increases lower oesophagal sphincter pressure, antral and duodenal contractions, gastric emptying of liquids and semi solids, and shortens the stationary phase for solids in the stomach.

Dosage
Adults: 20-40 mg , 3-4 times a day. In elderly commence at 10 mg
Children: 0.3 mg/ kg body weight, 3-4 times daily before meals and at bed time.

Contra- Indications: Pregnancy

Side Effects
The drug has certain side effects, that can affect individuals in different ways. The following are some of the side effects, that are often associated with the drug:

• Serum prolactin level may increase resulting in galactorrhoea in females & less frequently gynaecomastia in males.

Brands