Cefuroxime is an antibiotic resistant to most betalactamases and is active against a wide range of Gram-positive and Gram -negative organisms. The most important use of the drug is in treating meningitis caused by H. influenzae, meningcocci an pneumococcoi. This is so, because it attains high concentrations in C.S.F.

Dosage
Adults: 750 mg thrice daily i.m or i.v. Severe infections: 1.5 gm daily i.v. Total dose 3-6 gram daily
Children and infants: 30-100 mg/kg body weight daily in 3-4 divided doses.
Neonates: 100mg/kg body weight i.v. daily
This cephalosporin antibiotic can be administered orally and parenterally for treating respiratory, skin, and other infections.

Contra Indications: Patients with known hypersensitivity to cephalosporin antibiotics

Side Effects
The drug has certain side effects, that can affect individuals in different ways. The following are some of the side effects, that are often associated with the drug:

• Skin Rashes
• Eosinophilia
• Transient increase of hepatic enzymes

Pregnant and lactating mothers should use the drug with caution and after consulting a medical practitioner.

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